同种软骨移植后胶原含量变化的实验研究  

An experimental study on changes in collagen content after homologous cartilage implantation

作　　者：侯成群[1] 常晓峰[1] 杨壮群 王奕 许援朝[3] 杨小平[2] 郑信民[2] 

机构地区：[1]西安医科大学第一附属医院口腔科 [2]西安医科大学口腔医学院颌面整形外科,710004 [3]西安医科大学口腔医学院检验科生化室,710004

出　　处：《中华整形烧伤外科杂志》1995年第4期274-276,共3页

摘　　要：采用生化手段测定了豚鼠异体软骨移植后1～20周软骨胶原含量的变化,结果显示:术后第3周起软骨胶原含量开始下降,至第4周达最低点(P<0.05),此后逐渐回升,至第8周时已接近于正常组并维持在接近于对照组的水平(P>0.05)。提示可采用生化测定胶原在同种软骨移植后不同时期的含量变化来评价异体软骨移植后的结构和弹性变化。This experiment studied the changes in cartilage collagen content during 1～20 weeks after allografting of cartilage.The results showed that the collagen content was reduced beginning from the 3rd week,and reached the lowest point in the 4th week (P<0.05).Then it rose continuously and attained the normal level in the 8th week(P> 0.05).The study suggests that the changes in cartilage collagen content may help us to assess the cartilage structure and the elasticity after a cartilage allotransplantation.

关 键 词：软骨 软骨移植 胶原 生化分析 

分 类 号：R687.34[医药卫生—骨科学]