动物皮肤炎症病理模型的建立及五黄膏抗感染作用的实验研究  

The Establishment of Dermatitis Animal Models andThe Experimental Study of Anti-infection Effect ofWuhuang Oinmient

作　　者：魏领地[1] 苗培[1] 

机构地区：[1]北京市药品检验所

出　　处：《中药新药与临床药理》1995年第1期40-42,共3页Traditional Chinese Drug Research and Clinical Pharmacology

摘　　要：用表皮金葡菌涂于划痕皮肤表面，并皮内注入０．２ｍｌ菌原液可造成动物皮肤感染模型，感染部位有红肿发热现象。五黄膏可使红肿面积减小，与空白对照组相比有显著性差异（Ｐ＜０．０５）。皮内注入表皮金葡菌可造成小鼠皮肤感染引起死亡，五黄膏可降低小鼠因皮肤感染所致的死亡率（Ｐ＜０．０１）。By cutaneous scarification of Staphylococcus aureus and intradermal injection of 0.2ml bacterial liquid, a skin infection animal model with redness, swelling and hotness of the infected area was established. Application of Wuhuang Ointment can reduce the areas of infection . necrosis and cicartization and decrease the death rate, the difference being significant (P<0.01) as compared with the control group

关 键 词：五黄膏 药理学 金黄色葡萄球菌 动物模型 

分 类 号：R285.5[医药卫生—中药学] R965.1[医药卫生—中医学]