实验性心脏挫伤动物模型的建立  

THE ESTABLISHMENT OF EXPERIMENTAL ANIMAL MODEL OF CARDIAC CONTUSION

作　　者：官大威[1] 徐建青[1] 李德祥[1] 李庆生[2] 金鑫[3] 王怀良[3] 贾静涛[4] 

机构地区：[1]中国医科大学法医学系法医病理学教研室,沈阳110001 [2]中国医科大学法医学系刑事技术照像室,沈阳110001 [3]中国医科大学基础医学院药理学教研室,沈阳110001 [4]中国医科大学法医学系法医血清学教研室,沈阳110001

出　　处：《中国法医学杂志》1995年第2期65-67,共3页Chinese Journal of Forensic Medicine

摘　　要：本研究应用自制机械式弹性拉力打击器以9．1～10．5m／s速度冲击动物胸骨心前区，不仅导致左右心室压力、心电图及心率发生改变，而且造成了心脏挫伤等宏观的病理形态学变化，成功地建立了心脏挫伤动物模型，为深入研究钝力性心脏外伤奠定了基础。In the present study an experimental animal model of closed chest cardiac contusion in dogs was successfully established by impacting precardial area at the velocity of 9- 1 - 10. 5m/s with home-made elastic cord propelled impactor, After impact, some significant abnormalities of the left and right ventricular pressure,ECG and heart rate were recorded. Cardiac contusions were demonstrated at au-topsy. The establishment of the experimental cardiac contusion model could provide the tool for further study on nonpenetrating cardiac injury.

关 键 词：心脏挫伤 实验性动物模型 法医学鉴定 

分 类 号：R89[医药卫生—法医学]