人体腹膜孔淋巴引流单位的超微结构研究  

ULTRASTRUCTURAL STUDY ON HUMAN LYMPHATIC DRAINAGE UNITS IN PERITONEAL STOMATA OF HUMAN$

作　　者：李继承[1] 陈肖波[1] 章成伟[1] 钟灵健[1] 俞寿民 

机构地区：[1]浙江医科大学,浙江省人民医院

出　　处：《解剖学报》1995年第1期101-104,T018,共5页Acta Anatomica Sinica

基　　金：国家自然科学基金

摘　　要：用电镜和锇酸－二甲基亚砜－锇酸（ＯｓＯ_４－ＤＭＳＯ－ＯｓＯ_４，ＯＤＯ）冷冻断裂技术观察了人体腹膜孔淋巴引流单位的超微结构。淋巴引流单位位于腹膜孔内，由３种结构组成，即立方形间皮细胞、淋巴陷窝内皮细胞和两者之间的结缔组织。上述３种结构相互并置，但其间无特殊的连接结构。立方形间皮细胞常伸出瓣膜状胞质突起，使腹膜下小管呈蜿蜒曲折状。间皮下结缔组织中成纤维细胞的胞质突起可与淋巴陷窝内皮细胞相贴，而结缔组织的纤维层则横跨腹膜孔，形成腹膜孔的底和淋巴陷窝的顶。在这些纤维层中，纤维相互交织构成一个三维的结缔组织网。通过结缔组织网孔，使立方形间皮细胞与淋巴陷窝的内皮细胞相连，形成腹膜下小管。借助于腹膜下小管，腹膜腔与淋巴陷窝相通。腹膜孔淋巴引流单位位于腹膜腔物质吸收的必经之处，对物质的吸收起调节作用。Lymphatic drainage units(LDUs) may regulate the peritoneal stomata to uptake fluid, cells and particulate materials from the peritoneal cavity. The aim of this study is to elucidate the ultrastructure of human LDUs with ODO(OsO4-DMSO-OsO4 ) freeze fracture,with SEM and conventional TEM,The LDUs are located in the peritoneal stomata,and composed of three components:cuboidal mesothelial cells,endothelial cells of lymphatic lacunae,and intervening connective tissue. All these three components abut each other,but not linked by junctional specializations.The cuboidal cells often extend valve-like cytoplasmic processes which give the channels a tortuous course. The processes of fibroblasts are in contact with the endothelial cells of lacunae.A fibrous layer of connective tissue spans the floor of each stoma and forms the roof of each lacunae,The fibrous layer assembles into fiber bundles and forms a three-dimensional network.Through the connective tissue network the cuboidal cells and the lymphatic endothelial cells come into close contact with each other and form short channela.The channels connect the peritoneal cavitv with the lymphatic lacunae. The LDUs are important routes to regulate absorption activity from the peritoneal cavity.(Director of Department of Lymphology,Zhejiang Medical University,157 Yan An Road,Hangzhou 3l0006,China)

关 键 词：淋巴引流单位 腹膜孔 超微结构 

分 类 号：R322.492[医药卫生—人体解剖和组织胚胎学]