扑热息痛泡腾冲剂的研制  

The Research Granulae Effervescentes Paracetamoli

作　　者：孙殿甲[1] 李观海[1] 严风璋 陶亮[2] 王光充 黎明 阮红梅 

机构地区：[1]新疆医学院药学系 [2]新疆医学院第一附属医院药剂科 [3]乌鲁木齐市制药厂

出　　处：《新疆医学院学报》1989年第3期167-170,共4页

摘　　要：本文对扑热息痛泡腾冲剂的处方组成、生产工艺、药动学药效学、稳定性质量标准、临床效果进行了研究。结果表明扑热息痛泡腾冲剂处方工艺设计合理、性质稳定。与片剂比较,不但成人、小儿服用方便,而且起效快(p<0.01)、作用强(p 0.01),无副作用,总有效率为96.64％(p 0.0001),明显优于片剂。因此认为扑热息痛泡腾冲剂是安全、稳定、有效的新剂型。This paper studied the formulation of granulae effervescentes paraceta-moli, preparation process, pharmacodynamics, stability, quality guidelines and clinical result. The result indicates that the formulation of granulae effervescentes paracetamoli is reasonable and stabile. Comparing with tablet, the granulae effervescentes paracetamoli is not only convenient to the adult and baby but also producing a rapid action, powerful effection and no secondary action. The total effective ratio is equal to 96.64% and is better than tablets. Then we consider that granulae effervescentes paracetamoli is a safe stabile and effective dosage form.

关 键 词：扑热息痛 泡腾冲剂 处方组成 

分 类 号：R944.27[医药卫生—药剂学]