喉角化病的临床及治疗初探  

Preliminary study of laryngeal keratosis on pathogenesis and treatment

作　　者：曹海光[1] 张玉庚[1] 杨宝琦[1] 李志强[1] 

机构地区：[1]天津第二医学院附属第一中心医院耳鼻咽喉科

出　　处：《耳鼻咽喉（头颈外科）》1995年第2期79-81,共3页Chinese Arch Otolaryngology-Head Neck Surg

摘　　要：对３１例喉角化病的临床病理学观察结果表明，单纯角化病２０例，随访６例，１例复发；角化病伴非典型增生５例，随访３例，均发生癌变；角化病癌变１例，局部切除后６年健在；角化病伴鳞癌５例，全喉及部分喉切除后２例死亡。认为，声带长期磨擦损伤及咽喉粘膜干燥可能是导致角化病发生的主要原因。及时把握病变的性质及程度，给予恰如其分的治疗，可获得到满意的疗效。Abstract The pathogenesis and clinical feature in 31 patients of laryngeal keratosis on preliminary study were reported. Our patients popuration consisted of 28 males and 3 females ranging in age from 46 to 80 years. The pathologic types was simple laryngeal keratosis in 20 cases(bilateral in 4),keratosis with non-typical hyperplasia in 5 cases(bilateral in 2 ),laryngeal keratosis with carcinoma in 1 case(bilateral), laryngeal squamous cell carcinoma with kerato-sis in 5 cases(ipsilateral in 1,opposite in 1 , bilateral in 1, supraglottis in 1,posterior commis-sure in 1 ). Three of them(3 in 5)were stage Ⅳ. The vapour draw was used to treatment for patients of laryngeal keratosis, laryngectomy was for patients with laryngel carcinoma. 15 patients of laryngeal keratosis was follow-up 2 to 120 months, three of them were develop cancer. The pathogenesis, clinical feature and treatment were discussed.

关 键 词：喉疾病 治疗 外科手术 角化病 

分 类 号：R767.91[医药卫生—耳鼻咽喉科]