骨髓活检在预测MDS预后中的意义  

PROGNOSTIC SIGNIFICANCE OF BONE MARROW BIOPSIES IN MYELODYSPLASTIC SYNDROMES

作　　者：徐瑞容[1] 施敬芳[1] 陈唤青[1] 吴芳颐[1] 王迎春[1] 杨锦媛[1] 

机构地区：[1]南通医学院附属医院

出　　处：《白血病》1995年第2期88-90,共3页

摘　　要：报告２４例骨髓增生异常综合征骨髓活检结果与预后的关系，结果：骨髓活检与骨髓涂片所见大致相同，但前者对粒系、巨核细胞系病态造血诊断率更高，对ＡＬＩＰ及合并纤维化是唯一的诊断手段；活检时造血细胞中红系占优者预后好，粒系占优伴ＡＬＩＰ阳性者预后差，巨核细胞增生常伴骨髓纤维增生，预后亦差。Bone marrow biopsies were taken in 24 patients with myelodysplastic syndromes.There wascorrelation between the cellularity in the biopsy section and the marrow smears,but the biopsyhad higher diagnostic significance in morphologic abnormalities of granulocytic andmegakaryocytic series. Biopsy was the only way for diagnosis of ALIP and fibrosis,and thehypercellularity with predominance of erythrocytic lineage showed a favourable prognosis. Thepredominance of granulocytic series with ALIP positive indicated a bad survival. Proliferation ofmegakaryocytic lineage often accompanied with fibrosis and showed a poor prognosis.

关 键 词：骨髓增生异常 综合征 骨髓活检 预后 

分 类 号：R551.307[医药卫生—血液循环系统疾病]