海风藤酮及其类似物抗氧化活性研究  

STUDY ON ANTIOXIDANT ACTIVITIES OF LIGNANS,KADSURENONE AND BURCHLLIN

作　　者：沈传勇[1] 鲁纯素[1] 卢景芬[1] 韩桂秋[1] 马迎[1] 

机构地区：[1]北京医科大学物理化学教研室,北京医科大学天然及仿生药物重点实验室

出　　处：《北京医科大学学报》1995年第1期62-64,共3页Journal of Peking University(Health Sciences)

摘　　要：用自旋捕捉与自旋标记电子顺磁共振法研究发现海风藤酮及其类似物３５９－１１均有一定的抗氧化能力。对人红细胞膜的氧化性损伤有相当程度的保护作用，并与其结构有关。海风藤酮的作用强于３５９－１１。The antioxidant activities of lignans, kadsurenone and its analogue burchllin(359-11 )were investigated by using spin trapping and spin labelling ESR techniques.The results indicate that both compounds could scavenge active oxygen radicals,and protect human red blood cell membrane from oxidative damage.Their effects depend on their structures.The antioxidant activities of kadsurenone were stronger than those of burchllin.

关 键 词：海风藤酮 药理学 抗氧化剂 自由基清除剂 

分 类 号：R962[医药卫生—药理学]