氯乙烯对小鼠精子崎形的影响  

THE EFFECT OF VINY CHLORIDE ON THE MORPHOLOGY OF MOUSE SPERM

作　　者：云淑梅[1] 林慰慈[1] 沈惠麒[1] 

机构地区：[1]北京医科大学卫生毒理学教研室,北京医科大学劳动卫生教研室

出　　处：《北京医科大学学报》1995年第4期273-274,277,共3页Journal of Peking University(Health Sciences)

基　　金：国家自然科学基金

摘　　要：通过氯乙烯对小鼠精子形态的影响，探讨氯乙烯对生殖细胞的诱变性。结果表明，氯乙烯可诱发小鼠精子畸形率增加并呈现一定的剂量反应关系，氯乙烯所致小鼠精子畸形以香蕉形和无钩形为主。n this paper we observed the effect of vinyl chloride on the morphology of sperm,and assessed the muta-genicity of vinyl chloride on germ cells. The result showed vinyl chloride could increase the abnormal incidence of mouse sperm;the dose effect curves were obtained,and the main types of abnormal sperm induced by vinyl chloride were banana-like and non-hooked.

关 键 词：氯乙烯 精子 畸形 诱变性 小鼠 

分 类 号：R994.6[医药卫生—毒理学] TQ086.51[医药卫生—药学]