50例兔在体和离体器官组织射频介电性能的测量与分析  

IN VIVO AND IN VITRO DIELECTRIC PROPERTIES OF TISSUES FROM 50 RABBITS AT RADIO FREQUENCIES

作　　者：鲁勇军[1] 胡善明[1] 包玉生[1] 鲁飙 胡保卫[1] 余珏[1] 

机构地区：[1]中国医学科学院基础医学研究所生物医学工程室,北京100005

出　　处：《动物学报》1995年第4期387-392,共6页ACTA ZOOLOGICA SINICA

基　　金：国家自然科学基金资助项目;编号39100036。

摘　　要：根据同轴传输线反射原理，建立起计算机控制的生物组织介电测量系统；在６０—３０００ＭＨｚ频率范围对５０例兔器官组织进行了有效的在体和离体介电测量。测量结果的统计分析表明，不同兔器官组织之间介电参数的最大差异可达３０·４％；在体和离休测量得出的介电常数之间未见显著性差异，但电导率有频率依赖性的显著差异，因此将人体的离体介电参数延用到实际活体场合时，必须慎重。In this study, dielectric properties of tissues from 50 healthy rabbits, including muscle, liver, spleen and kidney were measured and analyzed in vivo and in vitro at frequencies from 60 to 3000MHz. An open ended coaxial line senior was employed in the measuring system composed mainly of a Network Analyzer (HP8753C) and a computer. The dielectric properties, permittivity and conductivity, were ca1culated from the measured reflection coefficient of the sensor. Statistical analysis of the experimental data of the tissues from 50 rabbits revealed that there were definite differences (5 %-30. 4 % ) among the dielectric data of these rabbit tissues partly due to their different water contents. The differences between the permittivities of these tissues, when measured in vivo and in vitro, were found to be within the experimental uncertainty. However, there were significant changes in the conductivity of excised tissues compared with that of in vivo tissues, which were statistically frequency dependent. This work suggests that one must be careful in using the in vitro dielectric properties of human tissues in the majority of engineering, diagnostic as well as therapeutic applications at Radio frequencies.

关 键 词：介电性能 器官组织 动物实验 兔 

分 类 号：R318.03[医药卫生—生物医学工程]