小鼠联会复合体畸变类型的电镜观察  

OBSERVATION OF SYNAPTONEMAL COMPLEX ABERRATIONS IN MALE MICE BY ELECTRON MICROSCOPY

作　　者：姜杰[1] 王彬[1] 王亚梅[1] 

机构地区：[1]白求恩医科大学放射医学研究所,东北师范大学生物系

出　　处：《辐射研究与辐射工艺学报》1995年第4期229-232,共4页Journal of Radiation Research and Radiation Processing

摘　　要：联会复合体和染色体一样，可以显示生殖细胞减数分裂过程中的诱变效应。采用雄性昆明种小鼠为实验材料，经４ＧｙＸ射线照射，于照后不同时间处死小鼠，制备联会复合体标本，并用电镜观察联会复合体畸变。除观察到常规染色体方法所见到的断裂、易位等畸变外；还观察到一些和联会有关的畸变类型，如银染桥、自身回折配对、联会紊乱，并探讨其和染色体畸变的关系，为今后研究生殖胞细遗传物质损伤提供一个新的方法。Synaptonemal complexes revealed mutagen-induced effects in germ cell meiotic chromosomes. Male mice were irradiated by 4 Gy X-rays and synaptonemal cytes were harvested at different time after exposure.Various form of synaptonemal complex aberrations were observed, such as breaks, rings, rearrangement which were consistent with those aberrations observed in metaphase I chromosome by conventional cytogenetic analysis. Some novel forms of synaptonemal complex aberrations were observed. The relationship between synaptonemal complex aberration and chromosome aberration was discussed.

关 键 词：电离辐射 联会复合体 畸变 染色体 放射损伤 

分 类 号：R818.74[医药卫生—放射医学]