人参多糖对X射线照射小鼠脾脏自由基含量的影响  

EFFECT OF POLYSACCHARIDES OF GINSENG(PSG) ON FREE RADICALS IN SPLEEN OF MICE EXPOSED TO X-RAY

作　　者：田生礼[1] 冯彪[1] 张启先[1] 董凤霞[1] 郑莹光[1] 

机构地区：[1]白求恩医科大学预防医学院,吉林大学测试中心

出　　处：《辐射研究与辐射工艺学报》1995年第4期246-248,共3页Journal of Radiation Research and Radiation Processing

摘　　要：采用电子自旋共振（ＥＳＲ）方法测定了照射前给予人参多糖３ｄ，对Ｘ射线照后小鼠脾脏自由基含量的影响。结果表明，（１）人参多糖可使３ＧｙＸ射线照射后小鼠脾脏自由基含量明显降低。（２）不同浓度（１２、２５０、５００ｍｇ·ｋｇ－１·ｄ－１）人参多糖对３Ｇｙ照射小鼠脾脏自由基含量均有明显的降低作用。（３）人参多糖对３Ｇｙ照射后６ｈ小鼠脾脏自由基含量降低最明显。提示，人参多糖可降低中等剂量Ｘ射线照射后早期小鼠脾脏中的自由基含量。The effects of PGS injection before total body X-irradiation on free radicals changes in spleen of mice were studied by means of ESR technique.The results showed that the contents of free radicals in spleen of mice injected with PSG before irradiation were lower than those of irradiation control group at 3Gy.Different concentration of PSG(125～500 mg/kg.d) could markedly decrease the contents of free radicals in irradiation group with 3Gy. While, free radicals in group with PSG 6 h, after irradiation were significantly lower than those irradiation control group. The results indicated that PSG could decrease free radicals in 3Gy X-rays irradiated mice especially for 3 hours after irradiation.

关 键 词：X射线 人参多糖 自由基 脾脏 辐射损伤 

分 类 号：R818.805[医药卫生—放射医学]