手性联萘胺衍生物为配体的铜络合物催化下某些烯烃的不对称环丙烷化反应  

Synthesis of Chiral Copper(Ⅱ)Complexes and Their Application in Asymmetric Cyclopropanation of Olefins

作　　者：陈光明[1] 陈馥衡[1] 周长海[1] 

机构地区：[1]北京农业大学应用化学研究所

出　　处：《高等学校化学学报》1995年第2期216-219,共4页Chemical Journal of Chinese Universities

基　　金：国家自然科学基金

摘　　要：以１，１＇－联萘－２，２＇－二胺为手性源合成了８对１６种光活性铜络合物，考察了它们对１，１－二苯乙烯、苯乙烯和２，５－二甲基－２，４－己二烯等３种烯烃的不对称环丙烷化反应的光学诱导活性。结果表明，以旋光活性联萘胺同水杨醛及２－羟基萘甲醛缩合而得到的Ｓｃｈｉｆｆ碱为配体的铜络合物的催化效果最佳。催化剂对２，５－二甲基－２，４－己二烯的催化效果优于其它两种烯烃。Sixteen chiral copper(Ⅱ) complexes derived from(R)-(+)-or(S)-(-)-2,2'-diamino-1,1'-binaphthyl(DABN) were synthsized.All the complexes were used as enentio selective catalysts in the asymmetric cyclopropanation reactions of 1,1-diphenylethylene, styrene and 2,5-dimethyl-2,4-hexadiene.It was found that the more effective catalysts are related to complexes with ligands prepared from optically active DABN and salicylaldehyde or 2-hydoxy-1-naphthylaldehyde.

关 键 词：联萘胺 烯烃 不对称 环丙烷化 铜配合物 

分 类 号：O625.12[理学—有机化学] O621.255.8[理学—化学]