单氮杂冠醚的合成及性质研究（Ⅱ）──两亲分子的合成及在水溶液中的自组织行为  

Studies on Synthesis and Property of Monoaza Crown Ethers(Ⅱ)──Synthesis of Amphiphiles and Self-assembly of the Amphiphiles in Aqueous Dispersion

作　　者：吴琳[1] 钱向平 邰子厚[1] 卞清 张进琪[1] 朱春生[1] 

机构地区：[1]南京大学化学系

出　　处：《高等学校化学学报》1995年第10期1550-1554,共5页Chemical Journal of Chinese Universities

摘　　要：以酰氯或酸酐与Ｎ－（３′－氨苯基）氮杂冠醚反应合成了一系列含长脂链基团的单氮杂冠醚两亲分子。电镜观测结果表明：系列两亲分子在稀溶液中均能自组织稳定的以双分子膜为基本结构的囊泡，其大小为３０～１５０ｎｍ，泡壁厚度为５～２５ｎｍ；并用ＵＶ－Ｖｉｓ和微量差示扫描量热研究了双分子膜中分子的聚集态和相变过程。A new series of amphiphilic monoaza crown ethers which contain aliphatic amido group were synthesized by the reaction of alkyloyl halide or acidic anhydride with N-(3′-aminophenyl)-azacrown. Transmission electron microscopy shows that these amphphiles can form the vesicles with diameters of 30-150 nm and their widths are 5-25 nm when dispersed in water. UV-Vis spectroscopy and differential scanning calorimetry were applied to examine the aggregate state and phase transition behavior of aqueous dipersions of these amphiphiles.

关 键 词：氮杂冠醚 两亲分子 自组织 双分子膜 

分 类 号：O626.5[理学—有机化学]