原发性高血压病因的多因素研究  

Multiple Etiology Study of Essential Hypertension

作　　者：刘蓬勃[1] 王学良[1] 徐慧文[1] 门伯媛[1] 徐祥麟 王祥庆 胡继新 纪华春 

机构地区：[1]西安医科大学流行病学教研室,710061 [2]陕西汉中心血管病研究所,723000

出　　处：《高血压杂志》1995年第4期316-318,共3页Chinese Journal of Hypertension

摘　　要：对39个家系父母二系三级亲属及无血缘关系亲属中15岁以上成人共937人高血压有关危险因素进行调查。资料经单因素分析、剂量效应分析及多因素非条件Logistic回归分析。结果表明,作为遗传标志的血缘关系与年龄、体重、饮酒、文化程度等5个因素对高血压发生有显著影响,这些因素可以认为是本次研究中高血压发病的主要危险因素。交互效应分析发现,两两因素相结合可出现相加模型的增效作用。We investigated some risk factors for hypertension in 39 probands and their first, second and third degree relatives as well as nonconsan-guineous relatives. The data were analysed by single factor analysis, dose-response relationship analysis and multivariate unconditional logistic regression analysis. The results showed:the risk factors related to the development of hypertension in our study were consanguineous relation, age, overweight, drinking, e-ducation status and occupation. In addition, an additive synergic model was found when the two risk factors were combined.

关 键 词：原发性 高血压 病因 多因素研究 

分 类 号：R544.102[医药卫生—心血管疾病]