妊娠血清锌、铜、铁、钙、镁FAAS测定及围产研究  

ANTENATAL INTERVENIENT RESEARCH AND DETERMINATION OF Zn,Cu,Fe,Ca,Mg IN PREGNANCY SERUM BY FAAS

作　　者：时彦[1] 陈维杰[1] 迟锡增[1] 董冬[1] 刘泽伦 孙永臻[1] 

机构地区：[1]北京师范大学化学系,中央广播电视大学化轻工系,北京医科大学附属人民医院,北京海淀妇幼保健院

出　　处：《北京师范大学学报（自然科学版）》1995年第1期91-94,共4页Journal of Beijing Normal University(Natural Science)

基　　金：国家"八五"攻关计划资助

摘　　要：应用火焰原子吸收光谱法（ＦＡＡＳ）直接测定不同妊周孕妇及婴儿脐血血清中微量元素含量，并以标准物牛血清作方法质控，监测结果有效地用于产前干预．在最佳实验条件下，各元素的精密度（ＳＲ）．检出限（ρＤＬ／ｍｇ·Ｌ－１）和标准加入回收率（Ｙ）分别为：Ｚｎ，４．１０％，９５６×１０－３，９９．０％～１０３％；Ｃｕ，３．５０％，０．０３７，９７．０％～１０１％；Ｆｅ，４．２７％，０．０４３，９９．０％～１０３％；Ｃａ，２．２９％，０．０２０，９９．０％～１０１％；Ｍｇ，２．２９％，３．８８×１０－３，９７．０％～１０３％．该方法具有用样量少、简便准确、高精密度等特点．A method for the direct determination of Zn,Cu,Fe,Ca,Mg in serum of pregnant women and infants during different gestational periods is described.To determine the reliability of the method,the standard ox serum is used.The analytical results are effectively used for antenatal intervence.Under the best experimental conditions,the relative standard deviations,the detective limit(mg·L-1and the recovery percentage of each element are:Zn 4.10%,9.56×10-3,99%～103%;Cu 3.50%,0.037,97%～101%;Fe 4.27%,0.043,99%～103%;Ca 2.29%,0.020%,99%～101%;Mg 2.29%,3.88 x 10￣-3,97%～103%.The method is simple,rapid,accurate and sensitive with a very little sample.

关 键 词：微量元素 血清 孕妇 产前干预 光谱分析 

分 类 号：R714.144[医药卫生—妇产科学] R446.11[医药卫生—临床医学]