Wistar大鼠血液生化值测定及性别和年龄对其影响的研究  

Determination of Hematological and Biochemical Values in Wistar Rats and Effects of Ages and Sexes on Them

作　　者：李善如[1] 耿志贤[1] 姜其辉 王冬平[1] 刘宝兴[1] 曾毅芳[1] 

机构地区：[1]军事医学科学院实验动物中心

出　　处：《北京实验动物科学与管理》1995年第1期11-14,共4页

摘　　要：用荷兰产ＩＳＰ半自动生化分析仪对不同性别四个年龄段的Ｗｉｓｔａｒ封闭群大鼠的１４项血液生化值进行了测定。和其他研究者的结果比较，该群大鼠具有较低的血液Ｈｂ、Ｔ．Ｂｉｌ、ＵＡ、Ｍｇ、ＴＧ值，较高的Ａｌｂ、Ｃｌ值。血液Ｃｒｅ、Ｃａ、Ｃｌ及４０－９０ｄ的ＴＰ值与人的正常值接近，ＢＵＮ、Ｐ　、Ｍｇ、ＴＧ值高于人的数值，除Ｃａ、ＣＨＯ值不受年龄和性别影响外（Ｐ＞０．０５），Ｃｌ、Ｔ、Ｂｉｌ分别不受性别、年龄的影响（Ｐ＞０．０５）；其它指标皆受性别、年龄两因素的影响。建议在实验中选择动物时，即要注意动物的来源，又要注意动物的性别和年龄，本群大鼠可作为研究人的某些血液生化值的模型。hematological and biochemical values of male and female Wistar rats at different ages were determined.Compared with those reported in the literatures, the result showed the rats had lower values of Hb T.Bil UA Mg,TG and higher values of Alb, Cl.Such values as Cre, Ca, Cl and 40-90d TP were within the ranges of human normal values, respectively.The values of BUN.P Mg, and TG were higher than those of human Neither ages nor sexes affected the values of serum Ca and CHO.No marked age differences of T. Bil and sexual differences of Cl occurred in the rats.Other values were markedly affected by ages and sexes When selecting animals in experiments it suggested that the species or breeds as Well as ages and sexes of them should be stressed.

关 键 词：WISTAR大鼠 血液生化值 实验动物 

分 类 号：Q95－331[生物学—动物学]