河南省司法系统职工HBV感染的血清流行病学研究  

STUDY TO RISK FACTORS FOR HBV INFECTION AMONG 1042 JUDICIAL POLICEMEN OF HENAN PROVINCE IN CHINA

作　　者：张建营[1] 王凯娟[1] 代丽萍[1] 周元方[1] 

机构地区：[1]河南医科大学流行病学教研室

出　　处：《河南医学研究》1995年第1期57-61,共5页Henan Medical Research

摘　　要：为了解我国司法干警乙肝病毒（ＨＢＶ）的感染状况和危险因素，１９９３年３月我们对河南省司法厅所属两单位１０４２名干警ＨＢＶ感染状况进行血清流行病学研究。检测方法使用酶联免疫法（ＥＬＩＳＡ）和固相放射免疫法（ＳＰ－ＲＩＡ）。结果发现，该人群ＨＢｓＡｇ、抗－ＨＢｓ、抗－ＨＢｃ阳性率和ＨＢＶ总感染率分别为４．８％、３３．４％、１７．０８％和４６．１％。从人群分布来看，ＨＢＶ感染存在有明显的性别差异。通过单因素和多因素分析发现，本人肝病史、家庭成员肝病史，注射史及不良的生活习惯（共用茶杯等）是该人群ＨＢＶ感染的重要危险因素。本研究结果提示，密切生活接触是ＨＢＶ感染不可忽视的因素，应予重视。In order to determine the risk factors for HBV infection among judicial police-men of China,a seroepidemiological study for HBV infection was carried out among 1042ju-dicial policemen in Henan Judicial Bureau in 1993. HBV markers were tested with enzymelinked immunosorbent assay ( ELISA)and solid phase radioimmunoassay(SP-RIA).Theprevalence rates of HBsAg、anti-HBs、 anti-HBc and HBV infection rate were 4.8%、33.4%、17.08%and 46.1%,respectively. There were statiscally significant differences in the preva-lence rates of HBV infection in persons of different sexes. With single factor analysis to riskof HBV infection to be as follows :the history of the individual hepatitis、the hepatitis historyof family members、the history of injection and the bad living habit. Using a stepwise regres-sion model for the multifactor analysis of risk factors,we also got a similar result.The resultof our study showed that the everyday living contact is still an important risk factor of HBVinfection. We considered that it was an effective measure of reducing HBV infection rate injudicial policemen of China to improve the sanitation of living environment and inoculate hep-atitis B vaccine.

关 键 词：感染率 乙型肝炎病毒 血清流行病学 

分 类 号：R512.620.1[医药卫生—内科学]