小儿重症肺炎血浆心钠素的变化  

MEASUREMENTS OF ATRIL NATRIURETIC PEPTIDE IN THE PLASMA OF CHILDREN WITH SEVERE PNEUMONIA

作　　者：程秀永[1] 王秀芳[1] 胡素君[1] 刘东峰[1] 贾莉婷[1] 

机构地区：[1]河南医科大学第三附属医院

出　　处：《河南医学研究》1995年第4期318-319,共2页Henan Medical Research

摘　　要：应用放射免疫分析法测定血浆心钠素（ＡＮＰ）浓度，普通肺炎３２例，重症肺炎４１例，正常对照３３例。结果：普通肺炎患儿血浆心钠素与正常对照差别不显著，而肺炎合并心力衰竭，肺炎合并呼吸衰竭和（或）中毒性脑病者，血浆ＡＮＰ显著升高（Ｐ＜０．００１），且恢复期较极期明显下降（Ｐ＜０．００１），接近正常水平。提示血浆心钠素对重症肺炎的诊断、转归判定有重要参考价值。Plasma atril natriuretic peptide(ANP) was measured in 32 cases of commonpneumonia,41 cases of severe pneumonia and 33 controls. The result shows that there was nosignificant difference in the plasma concentrations of ANP between the common cases and thecontrols.But the plasma ANP levels of severe cases,complicated with heart failure or respira-tory failure or toxic encephalopathy,were significantly higher than those of the controls anddecreased to normal level or so in the recovery period of pneumonia. The study indicates thatthe plasma ANP level is an important serum marker of diagnosis and prognosis in severepneumonia of children.

关 键 词：肺炎 心钠素 血浆 儿童 肺炎 

分 类 号：R725.631[医药卫生—儿科]