乐脂平治疗Ⅱ型糖尿病高脂血症的临床研究  

Effect of Olbetam on Hyperlipidemia in NIDDM

作　　者：余叶蓉 梁荩忠 张翔迅 

出　　处：《华西医科大学学报》1995年第4期427-429,共3页Journal of West China University of Medical Sciences

摘　　要：观察了３０例伴有高脂血症的Ⅱ型糖尿病患者用小剂量乐脂平（５００ｍｇ／ｄ）治疗４周后血清脂质、脂蛋白的变化。结果：血总胆固醇、甘油三酯及极低密度脂蛋白—胆固醇水平较治疗前下降，高密度脂蛋白—胆固醇明显升高，血糖、血肌酐及血尿酸无明显变化。服用该药未观察到不良反应，提示乐脂平能较好地改善糖尿病患者的脂代谢紊乱。Tbe effect of Olbetam on serumlipid and lipoproteins was studied in 30 diabetic pa-tients with hyperlipidemia in four weeks trial.Thedose of Olbetam was 500 mg/d. The results showedserum concentrations of TC,TG,and VLDL-C weredecreased while HDL-C especially HDL_2-C increasedsigniflcantly after treatment.There were no signifi-cant changes in FBG,blood creatinine and urine acid.This result suggests Olbetam can improve dyslipidemiain NIDDM and was well tolerated bv all patients.

关 键 词：降脂药 乐脂平 糖尿病 高脂血症 

分 类 号：R587.2[医药卫生—内分泌] R589.205[医药卫生—内科学]