髓鞘碱性蛋白在面神经再生室内修复中作用的初步观察  

A Preliminary Study of the Role of the Myelin Basic Protien upon the Rabbit Facial Nerve Regeneration within a Silicone Chamber

作　　者：骆文龙[1] 林代诚[1] 李永懋[1] 罗德儒 

机构地区：[1]华西医大附一院耳鼻咽喉科

出　　处：《华西医学》1995年第3期331-334,共4页West China Medical Journal

摘　　要：本文对外源性髓鞘碱性蛋白（ＭＢＰ）在３３只新西兰家兔面神经再生室内修复中的作用进行了初步观察。术后４、６及８周在光镜下行组织学观察，同时通过ＭＩＡＳ─２００图像分析仪对再生ＦＮ有髓轴突直径、面积、髓鞘厚度及再生有髓轴突数进行测量。结果表明ＭＢＰ具有促家兔面神经再生修复的作用，但其功能恢复及ＭＢＰ在活体内增强受损面神经再生的机制及ＭＢＰ促ＦＮ轴突再生的作用时间尚不清楚，有待进一步研究。A preliminary study of the role of exogenous myelin basic protein (MBP) was carried out in the neural repair of the facial nerve (FN) of adult New Zealand rabbit by using an in vivo preparation. The regenerated nerve from within the silicone chambers were dissected and fixed for histological studies by light microscopic level at 4,6 and 8 weeks, respectively, following the surgery. We studied the related FNs parameters (including diametrs of myelinated axons, thickness of myelin sheaths, and number of regenerated myelin axons, ect.) by using Imaging Analytical Instrument MIAS-200.Finally, we concluded that exogenous MBP within a silicone chamber at the time of entubational nerve repair enhanced regeration of myelinated axons across the sectioned ends of rabbits FNs.

关 键 词：髓鞘碱性 蛋白 面神经 再生室 修复术 

分 类 号：R651.305[医药卫生—外科学]