线索诱发海洛因依赖者渴求反应的性别差异  

THE GENDER DIFFERENCES OF CRAVING REACTION AND RELATED INDEXES ELICITED BY CUES IN HEROIN ADDICTS

作　　者：邵春红[1] 江开达[2] 赵敏[2] 徐一峰[2] 陆光华[2] 徐韩[2] 朱敏[2] 王秋颖[2] 

机构地区：[1]复旦大学附属华山医院精神科,上海200040 [2]上海市精神卫生中心,上海200030

出　　处：《中国药物依赖性杂志》2005年第3期208-211,共4页Chinese Journal of Drug Dependence

基　　金：上海市卫生局科技发展基金项目(01417)

摘　　要：目的:分析线索暴露对戒断期男女海洛因依赖者心理渴求程度及相关指标影响的差异。方法:222名男性和98名女性戒断期海洛因依赖者暴露于相关环境线索,根据被试者的自我报告,采用Likert分级评价线索诱发的渴求程度,填写主观戒断反应问卷、毒品使用情况和一般社会学资料。采用独立样本t检验,比较线索暴露诱发男女被试者渴求反应的差异。结果:线索暴露后,女性被试者诱发的渴求分值和主观戒断反应分值均高于男性(P<0·05,P<0·01),心率和瞳孔变化女性高于男性(P<0·01)。结论:环境线索诱发戒断期海洛因依赖者的渴求反应存在性别差异,女性渴求反应明显高于男性。Objective： To analyze the gender difference of cue- elicited heroin craving in abstinent heroin addicts. Methods： Heroin addicts 222 male and 98 females were exposed to heroin cue in a laboratory setting. Cue - elicited craving level was evaluated by Likert Scale according to self- report. All of the subjects filled out the questionnaire of subjective withdrawal syndromes, drug using and demographic information. The craving response between male and female was compared by independent sample t - test. Results ： After cue exposure, craving scores and subjective withdrawal syndromes in female were significantly higher than those in male （ P 〈 0.01 ）.Conclusion ： Gender difference of cue - elicited heroin craving exists. Females are more likely to report increasing craving in response to cue than males.

关 键 词：线索 诱发 海洛因依赖 渴求反应 性别差异 

分 类 号：R595.5[医药卫生—内科学]