HBV家庭内传播与小儿乙肝慢性化的关系  

RELATIONSHIP BETWEEN INTRAFAMILIAL HBV TRANSMISSION AND CHRO- NICITY OF HEPATITIS B IN CHILDREN

作　　者：林国贤[1] 赵汇川[1] 杜庆岭[1] 王根廷[1] 张光曙[1] 

机构地区：[1]解放军第88医院

出　　处：《解放军医学杂志》1994年第2期86-88,共3页Medical Journal of Chinese People's Liberation Army

摘　　要：本文报道１８９例小儿乙型肝炎，６４．１％为急性肝炎，３５．９％为慢性肝炎，家庭内直系亲属ＨＢＶＭ阳性者中有６７．８％为慢性肝炎，家庭内直系亲属ＨＢＶＭ阴性者中，仅１５．８％为慢性肝炎，两者相差非常显著（ｘ２＝５２．６９％，Ｐ＜０．０１）。７３．４％小儿慢性乙肝与ＨＢＶ家庭内传播有关。作者认为，ＨＢＶ家庭内传播与小儿乙肝慢性化有密切关系。This article reported 189 cases of child hepatitis B, and 64.1% of them were acute hepatitis while 35.1% were chronic hepatitis.In those whose parents＇ HBVM was poaitive, 67.8% were chronic hepatitis, while those whose parents＇ HBVM was negative, only 15.8% were chronic hepatitis, There existed a significant difference between the two groups （X^2= 52. 69; P〈0. 01）. In 73.4% of the ehildreN,chronic hepatitis B were related to intraFamilial HBV transmission, The authors believe that chronic hepatitis B of children is closely related to intrafamilial HBV tragsmission.

关 键 词：HBV 小儿 乙肝 慢性化 急性肝炎 

分 类 号：R512.62[医药卫生—内科学]