慢性乙型肝炎患者出院后远期转归  

LONG-TERM FOLLOW-UP OF CHRONIC HEPATITIS B PATIENTS AFTER DISCHARGE

作　　者：王志明[1] 陈伟华[1] 田琦琦[1] 李江[1] 李明山[1] 

机构地区：[1]解放军第260医院

出　　处：《解放军医学杂志》1994年第2期125-126,共2页Medical Journal of Chinese People's Liberation Army

摘　　要：慢性乙型肝炎患者８７例，含慢迁肝（ＣＰＨ）２２例，慢活肝（ＣＡＨ）５５例，肝硬变（Ｃｉｒ）１０例，均由肝活检病理确诊。经过７年追踪观察提示：肝功能异常１４例（１６．１％），其中ＣＰＨ４．５％（１／２２），ＣＡＨ２０％（１１／５５），Ｃｉｒ２０％（２／１０）；ＨＢｓＡｇ转阴率１２．３％（９／７３），ＨＢｅＡｇ转阴率７８．１％（２５／３２），抗ＨＢｃ转阴率６．３％（５／７９）；ＨＢｓＡｇ转阴多发生在第４～６年间（８／９），ＨＢｅＡｇ转阴性在第一年即发生，各年比较无明显差异。We have followed up 87 chromic hepatitis B patients for 7 years. Of them, 22 were chronic persistent hepatitis （CPH）, 55 were chronic active hepatitis（CAH）, 10 were circhosis（Cir）. All of them were diagnosed by liver biopsy. Liver funcrions were abnormal in 14 （16.1%） patients during follow-up. Among them, 1 was CPH（4.5%）, 11 were CAH（20%）. 2 were circhosis（20%）. During follow-up, in 9 of 7a（12.3%） HBsAg became negative, in 25 of 32（78.1%） HBeAg became negative, and in 5 of 79（6.3%） anti-HBc became negative. HEVsAg ,serocoversion occurred during the 4th to 6th years in most of the cases（8/9）. and HBeAg serocoversion occurred during the 1st to 7th years. There was no annttal difference.

关 键 词：慢性乙型肝炎 慢性迁延性肝炎 慢性活动性肝炎 肝硬变 消化系统 

分 类 号：R512.62[医药卫生—内科学]