加氢还原法合成邻氨基苯甲醚的工艺研究  

Synthesis of o-Anisidine by Hydrogenize Reduction

作　　者：曹晓群[1] 张成金 王萍[1] 刘爱军[1] 刘欣[1] 何志勇[1] 

机构地区：[1]泰山医学院化学与化学工程学院,泰安271000 [2]泰安高新区财源化工厂总工办,泰安271000

出　　处：《化工进展》2005年第7期767-769,共3页Chemical Industry and Engineering Progress

摘　　要：研究了用邻硝基苯甲醚催化加氢合成邻氨基苯甲醚,代替传统的硫化钠还原工艺。研究确定的最佳工艺条件为:反应温度80℃,反应压力0.7MPa,催化剂用量0.9%(以占邻硝基苯甲醚质量计),溶剂与邻硝基苯甲醚质量比为0.75∶1。加氢还原和硫化钠还原工艺比较,反应时间由6h缩短到1.75h,产品收率由90.5%提高到93.8%,解决了产生大量含硫废水的问题,产品成本可显著降低。o- Anisidine was synthesized by catalytic hydrogenation with o - nitroanisole, instead of traditional reduction by sodium sulfide. The optimum reaction condition was determined. The temperature of reaction was 80℃, the pressure of reaction was 0. 7 MPa, the amount of catalyst was 0. 9 % （based on the mass of o - nitroanisole）, and the mass ratio of solvent to o - nitroanisole was 0. 75 ： 1. Comparing with reduction by sodium sulfide, the time of reaction was decreased from 6 h to 1.75 h, and the yield was increased from 90. 5% to 93.8%. Furthermore, the problem of producing a great deal of sulfur - containing waste water was resolved. Production cost was reduced by ￥1650.

关 键 词：邻氨基苯甲醚 合成 制作工艺 加氢还原法 

分 类 号：TQ246.31[化学工程—有机化工]