年龄相关的运动功能减退神经机制研究:磁源性影像证据  

The study on age-related motor function degeneration: evidence from MSI

作　　者：黄力平[1] 赵振彪[2] 王佩云[1] 孙吉林[2] 吴杰[2] 李素敏[2] 吕振[1] 于俊海[1] 

机构地区：[1]天津体育学院运动人体科学系,天津300381 [2]河北省人民医院

出　　处：《中国康复医学杂志》2005年第7期504-506,i0001,共4页Chinese Journal of Rehabilitation Medicine

摘　　要：目的:应用磁源性影像技术探讨在简单视-运动任务活动时的脑增龄性变化神经机制。方法:本文应用磁源性影像技术对13例20—85岁右利手健康男性进行简单视-运动任务活动时脑磁信号时间和空间的表现进行研究。结果:青年组和老年组受试者双手运动潜伏期基本一致,左手平均55ms,右手59ms,差异无显著性意义;脑运动皮层定位显示为双侧手指运动区。高龄老年组运动潜伏期延长,非利手侧较利手侧延长更加明显,平均90—127ms;利手侧半球空间定位可见,而非利手侧半球未显示空间定位。结论:成年人随增龄所发生的运动功能减退主要发生在75岁以后高龄老年人;老年性脑改变导致脑功能普遍减退可能是成年人随增龄所发生的运动功能减退的神经机制之一;成年人随增龄所发生的运动功能减退以神经传导速度减慢和运动协调性差为特征;长期反复运动活动有利于延缓脑运动控制机能的减退速度。Objective：The neurology mechanism of motor aging was studied during simple first finger visual-motor activities by magnetic source imaging （MSI）.Method： Thirteen right-handed healthy volunteers （ male, 20-85 year sold） participated in the study. Their cerebral electromagnetic signal in both temporal and spatial sequence was measured when they were alternatively doing simple first finger visual-motor activities of left or right hand followinglight cadence being showed in front of the subjects.Result：No significant difference between the young and the elder group in movement latent periods of both hands was found, 55ms for the left hand, 59ms for the right hand, on average. The localizatlons of cerebral motor cortex fall down the finger regions of both sides. The movement latent periods of the senility group were prolonged, especially in the non-dominant hemisphere, 90-127ms for right side,Conclusion：Motor function degeneration with aging in adults mostly occurred in the senility which is older than 75 years old; the senile brain change is probably one of the neurology mechanism of motor aging; motor function degeneration is characterized of the slower nerve conduction and the dysfunction of motor coordination; prolonged, regular daily activities may prevent aging of motor-control system from speeding uo in senile time.

关 键 词：磁源性影像技术 运动功能减退 增龄 

分 类 号：R338[医药卫生—人体生理学]