原发性高血压患者动态脉压与心脏损害的关系  

Relationship between ambulatory pulse pressure and heart damage in essential hypertension

作　　者：柳淑云[1] 孙炎晨 林涛[1] 白荣杰[3] 

机构地区：[1]大庆市第四医院心内科,黑龙江大庆163712 [2]海林市柴河林业局职工医院,黑龙江海林157131 [3]北京世纪坛医院,北京100038

出　　处：《黑龙江医学》2005年第8期573-574,共2页Heilongjiang Medical Journal

摘　　要：目的探讨原发性高血压患者动态脉压与心脏损害的关系。方法选择原发性高血压患者62例,按动态脉压分为5.32～7.98kPa(40～60mmHg)组(n=29)和脉压>7.98kPa(60mmHg)组(n=33),对超声心动图左室质量指数、左室舒张末内径等指标进行组间对照分析。结果脉压>7.98kPa(60mmHg)组左室质量指数(114±17)g/m2、左室舒张末内径(50±4)mm均高于脉压5.32～7.98kPa(40～60mmHg)组(t=2.30,P<0.05;t=2.13,P<0.05)。心脏损害发生率高于脉压分为5.32～7.98kPa(40～60mmHg)组(52%和27%;t=2.48,P<0.05)。结论原发性高血压患者心脏损害与脉压有关,脉压增大是心血管事件的主要危险因素。Objective To explore the relationship between ambulatory pulse pressure and heart damage in essential hypertension.Methods 62 patients with primary hypertension were divided into two groups according to the levels of ambulatory pulse pressure [pulse pressure（pp） 5.32 - 7.98 kPa（ 40 - 60 mmHg）（ Group 1, n = 33） and pp 〉 7.98 kPa （60 mmHg）（ Group 2, n = 39） ]. Echocardiography was conducted to analysis according to left ventrieular mass index（ IVMI ） and left ventrieular end - diastolic diameter（LVEDD）. Results The LVMI（ 114 ± 17）g/m^2 and LVEDD（.50± 4）nan in group 2 were higher than those in group 1（ t =2.30, P 〈0.05; t =2.13, P 〈0.05）.The incidence of heart damage in group 1（52%）washigher thanthatingroup2（27%）（ t =2.48, P 〈0.05）.Conclusion Heart damageis related to pulse pressure in essential hypertension. Andtbe augmentation of pulse pressure is one of the risk factors of cardiovascular event.

关 键 词：内科学 高血压 脉压 超声心动图 

分 类 号：R541.2[医药卫生—心血管疾病]