紫外分光光度法测定复方松果体素胶囊中松果体素的含量  

Determination of Melatonin in Compound Melatonin Capsules by UV-spectrophotometry

作　　者：王中兰[1] 冯碧敏[1] 陈菊 

机构地区：[1]四川泸州医学院附属医院药剂科,泸州市646000 [2]四川泸州市药品检验所,泸州市646000

出　　处：《中国药房》2005年第15期1182-1183,共2页China Pharmacy

摘　　要：目的:建立以紫外分光光度法测定复方松果体素胶囊中松果体素含量的方法。方法:采用紫外分光光度法,检测波长为277nm。结果:松果体素检测浓度在5～25μg/ml范围内与吸收度线性关系良好(r=0.9996);平均加样回收率为96.49%(RSD=1.21%,n=6)。结论:本方法准确、可靠,操作简便,稳定性好。OBJECTIVE：To establish UV-spectrophotometry method for the determination of melatonin in the compound melatonin capsules. METHODS： The UV-spectrophotometry was adopted with the detection wavelength at 277nm.RESULTS：There was a good linear relationship between melatonin and its absorbability（r=0.9996） within the concentration range of 5～25μg/ml .The average recovery was 96.49% （RSD=1.21%, n=6） .CONCLUSION：The method is accurate, reliable,convenient and stable.

关 键 词：复方松果体素胶囊 松果体素 紫外分光光度法 含量测定 

分 类 号：R927.2[医药卫生—药学]