老年前期及老年人血脂代谢紊乱与中医证候的相关性研究  

Correlation between syndrome manifestations and metabolic disturbance of blood lipid in presenium and senium

作　　者：韩丽蓓[1] 杨惠民[1] 崔春燕 邢兆宏[3] 

机构地区：[1]北京中医药大学东直门医院,北京100700 [2]北京大学第一附属医院,北京100034 [3]首都医科大学附属北京朝阳医院,北京100020

出　　处：《北京中医药大学学报》2005年第4期77-79,共3页Journal of Beijing University of Traditional Chinese Medicine

基　　金：北京中医药大学科研基金课题

摘　　要：目的探讨老年前期及老年人血脂代谢紊乱与中医证候的相关性,且探讨中医证候与总胆固醇(TC)、甘油三酯(TG)、低密度脂蛋白胆固醇(LDL-C)、高密度脂蛋白胆固醇(HDL-C)、载脂蛋白A1(ApoA1)、载脂蛋白B(ApoB)之间的关系。方法调查100例高脂血症患者,记录一般情况(性别、年龄、身高、体重),调查中医证候,记录TC、TG、LDL-C、HDL-C、ApoA1、ApoB值。结果100例高脂血证患者中,痰浊阻遏证23例,脾肾阳虚证22例,肝肾阴虚证21例,阴虚阳亢证18例,气滞络瘀证9例,无证候7例;在各组中,痰浊阻遏证组TC、HDL-C最低,且与肝肾阴虚证组、阴虚阳亢证组有显著性差异。结论在各证型构成比中,以痰浊阻遏证组最多,占23%;气滞络瘀证组最少,占9%;痰浊阻遏证组主要表现为TG单项增高;肝肾阴虚证组、脾肾阳虚证组、阴虚阳亢证组、气滞络瘀证组表现为TC、TG双项升高。Objective To discuss the correlation between syndrome manifestations （SM） of Chinese medicine and metabolic disturbance of blood lipid in presenium and senium, and the relationship between SM and the levels of total cholesterol （TC）, triglyceride （TG）, low-density lipoprotein C （LDL-C）, high-density lipoprotein C （HDL-C）, apoliporotein A I （Apo A I ） and apoliporotein B （ApoB）. Method To investigate and record the general conditions （including sex, age, stature and weight） of 100 patients with hyperlipidemia, and their syndrome manifestations and levels of TC, TG, LDL-C, HDL-C, Apo A I and ApoB. Results There were 23 patients with the syndrome of phlegm-turbidity stagnation （group 1）, 22 with the syndrome of spleen-kidney yang deficiency （group 2）, 21 with the syndrome of liver-kidney yin deficiency （group 3）, 18 with the syndrome of yin deficiency with exuberant yang （group 4）, 9 with the syndrome of qi stagnation and collateral stasis （group 5）, and 7 without any syndromes （group 6）. The levels of TC, HDL-C in group 1 was the lowest compared with other groups, and had a significant difference compared with group 3 and 4. Conclusion In the constitutional proportion of syndrome type, group 1 was 23 % （the highest） and group 5 was 9 %（the lowest）. The level of TG was a unipolar increase in group 1 and the levels of TC and TG were diphasic increases in group 2, 3, 4 and 5.

关 键 词：辨证分型 高脂血症 相关性研究 

分 类 号：R259.892[医药卫生—中西医结合]