部分性脾栓塞术在原发性肝癌合并脾功能亢进中的临床价值  

The clinical value of partial splenic embolization for patients with liver cancer and hypersplenism

作　　者：盛玉国[1] 王文明[1] 王保华[1] 李乃选[1] 荆秀荣[1] 段新武[1] 

机构地区：[1]滨州医学院附属医院介入医学科,滨州市256603

出　　处：《滨州医学院学报》2005年第4期243-244,共2页Journal of Binzhou Medical University

摘　　要：目的探讨部分脾栓塞术在原发性肝癌合并脾功能亢进中的临床应用价值。方法应用聚乙烯醇(PVA)颗粒及碘化油对29例原发性肝癌合并脾功能亢进患者实行部分脾栓塞术及肝动脉化疗栓塞术,随访术后疗效、患者血象变化及对患者的影响。结果29例原发性肝癌合并脾功能亢进患者均成功实施了部分脾脏栓塞术和肝动脉化疗栓塞术,消除了脾亢症状,白细胞和血小板术后24h即有明显提高(P<0.05),延长了生存时间,无严重并发症发生。随访6～21个月,脾功能亢进症状未见复发。结论部分性脾栓塞术简便、微创、安全,治疗原发性肝癌合并脾功能亢进疗效好。Objective To study the clinical efficacy of partial splenic embolization（PSE） for patients with liver caner and hypersplenlsm. Methods 29 patients with liver cancer had a PSE procedure for hypersplenism. Different periods of follow-up results were evaluated in all patients,blood flow velocity of portal and splenic veins were compared respectively between pre- and post-embolization procedure. Results The procedure was successful technically and hypersplenism was improved in all patients. No severe complication was occurred. And platelet counts and leukocytes improved significantly after 24 hours of procedure in most patients and normal or keeping high serum level throughout the follow-up period after 4 weeks in all patients. Blood flow velocity of portal and splenic veins decreased significantly（ P 〈 0.05）. In the period of 6～21 months follow-up, no patient had recurred hypersplenism. Conclusions PSE procedure is minimal invasive. It is safe and effective for patients with liver cancer and hypersplenism.

关 键 词：脾功能亢进 原发性肝癌 脾栓塞术 

分 类 号：R815[医药卫生—放射医学]