SD大鼠苯中毒模型的建立与检测  

Establishment of a model of benzene toxicosis in SD rats

作　　者：詹纯列[1] 肖育华[1] 吴锦银 李建军[1] 杨传红[1] 李新春[1] 

机构地区：[1]广州军区广州总医院医学实验科,广东广州510010 [2]广州市防疫站

出　　处：《西南国防医药》2005年第2期131-133,共3页Medical Journal of National Defending Forces in Southwest China

摘　　要：目的:建立SD大鼠苯中毒模型。方法:苯溶液多点皮下注射。结果:模型鼠血液学变化符合人苯中毒国家诊断标准变化趋势。结论:该方法建立的SD大鼠苯中毒模型可用于苯中毒疾病研究。Objective： To establish a model of benzene toxicosis in rats. Methods： The tested SD rats were injected subcutaneously with benzene solution at different sites. Results： The changes of hematological parameters of these animals corresponded with the national diagnostic criteria of benzene toxicosis in human body. Conduslon.. This model is successful and may be used to study benzene toxicity for human body.

关 键 词：苯 中毒 SD大鼠 模型 

分 类 号：R979.7[医药卫生—药品]