肝豆状核变性并发脾功能亢进脾切除前后骨髓象变化  

Study on myelogram of patients with Kinnier-Wilson syndrome companied by hypersplenia pre-or post-splenectomy

作　　者：韩宁林[1] 

机构地区：[1]安徽中医学院第一附属医院,安徽合肥230031

出　　处：《罕少疾病杂志》2005年第4期21-23,共3页Journal of Rare and Uncommon Diseases

摘　　要：目的探讨肝豆状核变性并发脾功能亢进脾切除手术前后的骨髓象变化。方法回顾性分析我院2002年6月～2004年12月脾切除治疗肝豆状核变性合并脾功能亢进9例患者的临床资料。结果9例中男6例,女3例,年龄11～32岁。均于切脾前1周及切脾后2周各行骨穿1次。术后9例患者外周血全血细胞均有不同程度的升高;1例溶血性骨髓象完全恢复正常,3例中性粒细胞胞浆中中毒性颗粒减少,核分叶过多现象消失;巨核细胞数量正常。结论肝豆状核变性并发脾功能亢进患者脾切除前后的外周血象及骨髓象有明显变化。脾切除有利于肝豆状核变性患者的进一步治疗。Objective To analyze the myelogram of patients with Kinnier-Wilson syndrome companied by hypersplenia pre- or post-splenectomy. Methods The clinical data of 9 patients with Kinnier-Wilson syndrome companied by hypersplenia, which underwent splenectomy,were studied retrospectively. Results Of 9 patients, 6 were male and 3 were female. The patients＇ age ranged from 11 to 32 years. One week before or 2 weeks after splenectomy,bone puncture was performed in 9 patients. Both hemogram and myelogram of 9 patients were changed greatly. Conelusion The splenectomy is benefit for advanced treatment of the patients with Kinnier-Wilson syndrome companied by hypersplenia.

关 键 词：肝豆状核变性 脾功能亢进 脾切除 骨髓象 

分 类 号：R551.1[医药卫生—血液循环系统疾病] R657.63[医药卫生—内科学]