100Hz振动对尾部悬吊大鼠比目鱼肌纤维超微结构的影响  

Effects of 100 Hz Vibration on Ultrastructure of Soleus Muscle in Tail-suspended Rats.

作　　者：杨威[1] 樊小力[1] 宋新爱[1] 

机构地区：[1]西安交通大学医学院生理学教研室,陕西西安710061

出　　处：《航天医学与医学工程》2005年第4期259-261,共3页Space Medicine & Medical Engineering

基　　金：国家自然科学基金资助(30070830)

摘　　要：目的观察100Hz振动对尾部悬吊大鼠比目鱼肌(SOL)梭内、外肌纤维超微结构的影响。方法采用大鼠尾部悬吊法建立模拟失重模型。高频正弦波振动SOL。用透射电镜观察比较振动组和非振动组吊尾7d大鼠SOL梭内、外肌纤维超微结构的变化。结果吊尾7d后大鼠SOL梭内、外肌纤维的超微结构明显改变,而在模拟失重期间给予高频正弦波振动的SOL梭内、外肌纤维超微结构变化不明显结论高频正弦波振动对模拟失重大鼠SOL梭内、外肌纤维超微结构的改变有明显对抗作用。Objective To study the effects of 100 Hz vibration on ultrastructure of intrafusal and extrafusal fibers in soleus muscle of tail-suspended rats. Method Weightlessness was simulated by tail suspension of female rats. The ultrastructure of intrafusal and extrafusal fibers of soleus muscle were examined after exposure to 100 Hz vibration. Result The ultrastructure of intrafusal and extrafusal fibers of soleus muscles showed obvious retrograde changes after 7d tail suspension, whereas these changes were not obvious after ？ d tail suspension plus 100 Hz vibration. Conclusion High frequency vibration can counteract the effect of simulated weightlessness on ultrastructure of intrafusal and extrafusal fibers in soleus muscles of rats.

关 键 词：失重模拟 尾吊 高频振动 超微结构 梭内肌纤维 梭外肌纤维 比目鱼肌 

分 类 号：R852.22[医药卫生—航空、航天与航海医学]