藏药湿生扁蕾的化学成分研究  

Studies on chemical constituents from Gentianopsis paludosa

作　　者：王焕弟[1] 谭成玉[1] 杜昱光[1] 白雪芳[1] 林炳承[1] 

机构地区：[1]中国科学院大连化学物理研究所,辽宁大连116023

出　　处：《中国药学杂志》2005年第14期1059-1061,共3页Chinese Pharmaceutical Journal

摘　　要：目的对湿生扁蕾全草进行化学成分研究。方法用柱色谱法分离化学成分,波谱法鉴定其结构。结果分离得到8 个化合物,分别为三十烷醇(Ⅰ),齐墩果酸(Ⅱ),熊果酸(Ⅲ),1-羟基齐墩果酸(Ⅳ),kaneric acid(V),木犀草素(Ⅵ),木犀草素-7-O-β-D-葡萄糖苷(Ⅶ),7,8-二羟基-3-甲氧基(?)酮-1-O-β-D-葡萄糖苷(Ⅷ)。结论化合物Ⅰ,Ⅱ,Ⅳ,Ⅴ,Ⅶ,Ⅷ为首次从该植物中分离得到,其中化合物Ⅷ为首次从扁蕾属植物中分离得到,Ⅴ为首次从龙胆科植物中分离得到,Ⅳ为首次从天然产物中分离得到。OBJECTIVE To study chemical constituents from Gentianopsis paludosa.METHODS Colunm chromatogrophy and spectral analysis were used to isolate and identify the constituents, respectively. RESULTS Eight compounds were isolated and identified as triacontanol（ Ⅰ ）, oleanolic acid（ Ⅱ ）, ursolic acid（ Ⅲ ）, 1-hydroxyoleanolic acid（ Ⅳ ）, kaneric acid （Ⅴ）, luteolin（ Ⅳ ）, luteolin-7-O-β-D-glucoside（ Ⅴ ）, 7,8-dihydroxy-3-methoxyxanthone - 1- O-β- D-glucoside（ Ⅵ ）. CONCLUSION Compound Ⅰ , Ⅱ, Ⅳ, Ⅴ, Ⅵ and Ⅶ are isolated from the plant for the first time. In addition, the compound Ⅷ,Ⅴ and Ⅳ are isolated from Gentianopsis, Gentianaceae and natural product for the first time, respectively.

关 键 词：温生扁蕾 化学成分 

分 类 号：R282.6[医药卫生—中药学]