广西地区64例人免疫缺陷病毒感染及艾滋病感染患者口腔病损的临床观察  

Investigation on Oral Lesions in 64 Chinese HIV/AIDS Patients in Guangxi Province

作　　者：陶人川[1] 邓华颉[1] 牙祖科[1] 郭素贞 梁树雄 刘伟 

机构地区：[1]广西医科大学口腔医院口腔内科 [2]广西区疾病控制中心,广西南宁530021

出　　处：《华西口腔医学杂志》2005年第4期338-340,共3页West China Journal of Stomatology

基　　金：国家自然科学基金资助项目(30160087);广西青年科学基金资助项目(桂科青0144029)

摘　　要：目的了解广西人免疫缺陷病毒感染及艾滋病感染(HIV/AIDS)患者口腔病损状况,为我国HIV/AIDS人群口腔疾病的防治提供依据.方法以经广西区疾病控制中心确诊为HIV/AIDS患者64例为调查对象,由专业人员采集病史,进行口腔专科检查,并将详细记录的结果与世界卫生组织艾滋病感染口腔表征协作中心制定的艾滋病口腔表征分类及诊断标准相比较.结果64名HIV/AIDS患者,年龄范围为5月～64岁,平均年龄36.1岁,其中男53人,女11人.48名有口腔主诉,以口干、疼痛、吞咽困难为主;口腔表现为口腔念珠菌病39例、口干症20例、口腔溃疡11例、艾滋病相关的牙周病7例、单纯疱疹病毒感染口炎6例、带状疱疹3例、口腔毛状白斑2例、卡波济肉瘤和淋巴节炎各1例.结论口腔念珠菌病是HIV/AIDS患者最常见的口腔表征,多数患者伴有口干、唾液分泌减少.口腔溃疡患病率与正常群体相比没有提高,但是溃疡严重程度增加.提示HIV/AIDS患者常伴有口腔表征,并且部分口腔表征出现较早.Objective To investigate the prevalence, age and gender distribution and clinical featutes of HIV/AIDS oral lesions in patients in Guangxi province, and to provide the epidemiological information for prevention and treatment of these diseases in the certain population. Methods A total of 64 HIV/AIDS patients were included in this study. All patients HIV serum-status was confirmed in Guangxi Center of Disease Control （ GXCDC ）. Oral examination was carried out by standardized specialists.HIV/AIDS orofaeial lesions were recorded and diagnosed using the EC Clearing House Criteria on Oral Problems related to HIV Infection （1992）. Results Among the total of 64 HIV/AIDS patients included in this study, there were 53 males and 11 females,with mean age of 36.1 years. Candidiasis was the most common lesion with the pseudomembranous type predominating. High prevalences of xerostomia, 11 oral ulceration and 7 HIV related periodontitis were noted. 6 Herpetic stomatitis and 3 herpes zoster, 2 oral hairy leukoplakia and 1 Kaposi＇s sarcoma and 1 lymphadentitis also were found. Conclusion This study shows a high prevalence of candidiasis, salivary gland disease. Maybe oral ulceration prevalence is not increased, but lesion severity is increased with more severe heperiform or major RAU. It suggested that HIV/AIDS usually shows oral lesion and partly can appear in early phase.

关 键 词：艾滋病 口腔表征 念珠菌病 

分 类 号：R512.91[医药卫生—内科学]