快速检测B型利钠肽用于早期诊断充血性心力衰竭  

Rapid measurement of B-type natriuretic peptide in the emergency diagnosis of heart failure

作　　者：王劲[1] 闫卫利[1] 王静[1] 郑刚[1] 

机构地区：[1]天津市第三医院,天津300250

出　　处：《中国心血管杂志》2005年第4期293-295,共3页Chinese Journal of Cardiovascular Medicine

摘　　要：目的探讨快速检测B型利钠肽(BNP)对充血性心力衰竭(CHF)的早期诊断价值。方法对128例以呼吸困难为主诉,疑似心力衰竭的患者进行快速测定BNP,并与随后进行超声心动描记术、胸部X线等常规检查作比较。结果BNP浓度与心力衰竭严重程度相关,BNP≥100ng/L诊断心力衰竭的灵敏度为93.9%,特异性为91.7%,阳性预测值为92.5%,阴性预测值为93.2%。而超声心动描记术、胸部X线诊断心力衰竭的阳性率分别为71%和64%,与BNP相比均有显著性差异。结论快速测定BNP有助于早期诊断或排除心力衰竭,BNP值是最好的诊断心力衰竭的指标。Objective To investigate the value of rapid bedside assay of B-type natriuretie peptide（ BNP/） in early diagnosis of heart failure. Methods BNP levels were obtained from 128 patients with dyspnea. Compare with the results of the following echocardiogram and chest X-ray. Results BNP levels correlated with the degree of the heart failure. BNP level≥100ng/L, the diagnostic sensitivity of BNP was 93.9 % and specificity was 91.7 %, with a positive and negative predictive value of 92.5 % and 93.2 % respectively; the positive rate of eehocardiogram and chest X-ray were 71% and 64 % respeetively. There were signficat differenee in the positive rates of BNP, eehoeardiogram and chest X-ray. Conclusions Rapid BNP assay may be helpful in diagnosis of heart failure. BNP is a stronger independent predictor of heart failure thanother clinieal indicator.

关 键 词：B型利钠肽 充血性心力衰竭 诊断 

分 类 号：R541.61[医药卫生—心血管疾病]