新生儿窒息心脏收缩时间间期变化与临床表现及预后的关系  

Changes of systolic time interval after neonatal asphyxia and ist relationship with clinical manifectation and prognosis

作　　者：刘金香[1] 石军[2] 

机构地区：[1]山东省临沂市人民医院,山东临沂276003 [2]山东临沂医学专科学校,东临沂276002

出　　处：《宁夏医学杂志》2005年第8期539-541,共3页Ningxia Medical Journal

摘　　要：目的观察窒息新生儿心脏收缩时间间期(STI)的变化,探讨其与临床表现及预后的关系。方法利用二维及多普勒超声对27例轻度窒息、18例重度窒息及14例正常新生儿进行二维超声及STI测定,并分析其与临床表现及预后的关系。结果和正常新生儿比较,轻、重度窒息组心脏的腔室大小和室壁厚度无变化(P>0.05)。轻、重度窒息组与正常新生儿相比,急性期右室射血时间(RVET)缩短(P<0.05);重度窒息新生儿右室射血前期时间(RPEP)延长。重度窒息新生儿RPEP/RVET急性期和恢复期均较正常和轻度窒息新生儿增大(P<0.05)。急性期重度窒息新生儿较正常新生儿的左室射血前期时间(LPEP)有所延长(P<0.05)。急性期和恢复期重度窒息组RPEP/RVET增大者较轻度窒息组增多,急性期RPEP/RVET增大者心衰发生及远期致残率较RPEP/RVET正常者增加。结论窒息对新生儿心功能的影响右心重于左心。RPEP/RVET增大者临床表现较重,发生残疾的可能性较大。Objective To observe changes of systolic time interval（STI） after neonatal asphyxia and explore its relationship with clinical manifestation and prognosis. Methods Tow - dimensional and doppler echocardiography was employed to detect tow - dimension parameters and left and right ventricular STI in 27 mild and 18 severe asphyxiated neonates as well as 14 normal controls and its relationship with clinical manifestation and prngnosis in neonates with asphyxia was analyzed. Results There was no difference in cavity and thickness of heart and great arteries between normal and asphyxiated neonates. In acute stage mild and severe asphyxiated neonates have a shorter right ventricular ejection time （RVET） than normal neonates and a longer right ventricular preejection period（RPEP） was found in severe neonates than that in normal and mild asphyxiated neonates. Left ventricular preejection time（LPEP） was prolonged in comnparison with normal neonates in ccute stage and convalescence. There were more cases with increased RPEP/RVET in severe asphyxiaed group than those in mild and normal group in acute stage. The incidence of failure in acute stage and disability in late period was higher in cases with increased RPEP/RVET than those with normal RPEP/RVET. Conclusion Asphyxia had more severe damage to right ventricle than that to left ventricle. Cases with increased RPEP/RVET is prone to suffering from heart failure in acute stage and more likely to undergo disability in late period.

关 键 词：婴儿 新生 心脏收缩时间间期 窒息 超声心动图 

分 类 号：R722.12[医药卫生—儿科]