妊娠期肝内胆汁瘀积症孕妇肝功能指标与围生儿预后的关系  

Relationship of gravida's liver function with the perinatal prognosis in ICP patients

作　　者：王冬梅[1] 李新玲[1] 

机构地区：[1]安徽省合肥市第一人民医院妇产科,安徽合肥230061

出　　处：《安徽医药》2005年第8期608-609,共2页Anhui Medical and Pharmaceutical Journal

摘　　要：目的探讨妊娠期肝内胆汁瘀积症(ICP)孕妇肝功能指标与围生儿预后的关系.方法对2002年1月～2003年12月安徽省合肥市第一人民医院218例ICP孕妇肝功能指标及围生儿预后进行回顾性分析.结果孕妇肝汁酸(TBA)及胆红素(BIL)水平升高者胎儿窘迫及羊水粪染发生率增加,孕妇血清丙氨酸转氨酶(ALT)、门冬氨酸转氨酶(AST)升高程度与胎儿窘迫率及羊水粪染率无关.结论ICP孕妇妊娠期TBA及胆红素水平升高程度高者胎儿预后不佳,必须高度重视,适时剖宫产终止妊娠将明显改善围生儿预后.Aim To investigate the relationtship of gravida＇s liver function with the perinatal prognosis in ICP patients. Methods Retrospective analysis of gravida＇s liver function and the peoinatal prognosis in 218 ICP patients which were delivered in Hefei First People＇s Hospital between 2001 ,Jan and 2003, Dec. Results ICP patients, higher level of the Total bile acid （TBA） and bilirubin （BIL） results in higher incidence of the fetal distress and amniotic fluid contamination, while the level of ALT （alanine aminotransferase） and AST （aspartate aminotransferase） has nothing with the fetal distress and amniotic fluid contamination. Conclusion We should pay much attention to these patients who have high level of TBA and BIL. Taking a uterlne-incision delivery to terminate pregnancy could be significantly improve the perinatal prognosis.

关 键 词：肝内胆汁瘀积症 胆汁酸 胆红素 孕妇 胎儿 妊娠期肝内胆汁瘀积症 围生儿预后 肝功能指标 合肥市第一人民医院 血清丙氨酸转氨酶 

分 类 号：R714.7[医药卫生—妇产科学]