血管迷走性晕厥儿童血管内皮功能的彩色多普勒超声检测  

Endothelial function in children with vasovagal syncope via color Doppler flow imaging.

作　　者：张清友[1] 杜军保[1] 李源[1] 艾乙[1] 

机构地区：[1]北京大学第一医院儿科,100034

出　　处：《中国实用儿科杂志》2005年第8期482-484,共3页Chinese Journal of Practical Pediatrics

基　　金：首都医学发展基金资助(2002-3037);国家十五攻关计划(2004BA720A10)

摘　　要：目的应用多普勒超声显像法探讨血管迷走性晕厥(VVS)儿童的血管内皮功能。方法研究对象共20例,均为2002年1月至2003年12月在北京大学第一医院儿科就诊儿童,分为VVS组(n=10)及非VVS对照组(n=10),对10例经直立倾斜试验确诊的血管迷走性晕厥儿童,应用多普勒超声测定肱动脉的血流介导的血管舒张反应,并与10例经直立倾斜试验除外VVS的对照组儿童进行比较。结果两组患儿的年龄、性别、身高、体重、基础血压及基础肱动脉血管内径均无显著性差异,但血管迷走性晕厥儿童的血管内皮依赖性舒张功能较对照组显著增强[(11.93±4.46)%vs(8.46±2.18)%,P<0.05]。结论血管内皮依赖性舒张功能增强可能是儿童血管迷走性晕厥发生机制之一。Objective To investigate artery endothelial tunction in children with vasovagal syncope via color Doppler flow imaging. Methods Ten patients with vasovagal syncope diagnosed by head-up tilt test were selected as study group and another ten patients without vasovagal syncope （ excluded by the same test） were selected as control group. Endothelial function of all children was detected by measuring endothelium-dependent flow-mediated vasodilation of brachial artery with color Doppler flow imaging system. Results There were no significant difference in age, gender, stature, body weight,baseline blood pressure and baseline brachial artery diameters between the two groups. Flow-mediated vasodilation in children with vasovagal syncope were significantly greater than those in controls, （ 11.93 ± 4.46 ） % vs （ 8.46 ±　2. 18 ） % , P 〈 0. 05 ）. Conclusion Augmented endothelium-dependent vasodilation may play an important role in children with vasovagal syncope.

关 键 词：晕厥 血管迷走性 儿童 血管内皮功能 超声显像 

分 类 号：R72[医药卫生—儿科]