肝脏灌注成像的CT扫描方法及应用价值  

The Method and Application of Hepatic Perfusion Imaging with Helical CT

作　　者：谢红波[1] 江利[1] 杨建勇[1] 杨旭锋[1] 严超贵[1] 李子平[1] 

机构地区：[1]中山大学附属第一医院放射科,广州510080

出　　处：《放射学实践》2005年第8期673-675,共3页Radiologic Practice

摘　　要：目的:探讨单层CT动态增强扫描测定肝硬化肝脏血流量的扫描方法及其应用价值。方法:15例经临床、实验室及B超检查诊断为肝硬化的患者,其中ChildB级患者10例,ChildC级患者5例。对照组为13例无肝脏疾病的患者。所有患者均选取同时含有肝脏、脾脏、主动脉和门静脉的层面进行单层CT动态增强扫描,绘制感兴趣区时间密度曲线,计算各血流灌注参数。结果:单层CT动态增强扫描测量肝组织的肝动脉灌注量(HAP)、门静脉灌注量(PVP)、总肝血流量(THBF)和肝动脉灌注指数(HPI)。正常组的HAP、PVP、THBF和HPI分别为(0.28±0.10)ml/min·ml、(1.18±0.40)ml/min·ml、(1.46±0.44)ml/min·ml和(19.73±5.81)%;肝硬化组的HAP、PVP、THBF和HPI分别为(0.23±0.11)ml/min·ml、(0.61±0.25)ml/min·ml、(0.84±0.32)ml/min·ml和(27.16±12.75)%。结论:肝脏单层CT灌注成像,可定量测定各项肝脏血流灌注参数,对肝硬化患者的量化诊断有一定的参考价值。Objective：To estimate hepatic perfusion parameters with helical CT. Methods：Dynamic single-section computed tomography （CT） of liver was performed in 15 liver cirrhosis patients and 13 normal subjects. In accordance with the Child-Pugh classification, 10 with Child B.and 5 classified with Child C. CT scans were obtained at a single level to include the liver, spleen,aorta,and portal vein. On each CT scan,time-density curves were described to calculate the hepatic perfusion parameters. Results： Hepatic perfusion parameters including hepatic artery perfusion,portal venous perfusion,total hepatic blood flow and hepatic perfusion index could be measured with dynamic single-section helical CT. Conclusion：Dynamic single-section CT shows potential in quantifying hepatic perfusion parameters.

关 键 词：肝脏灌注成像 体层摄影术 X线计算机 应用价值 CT扫描 

分 类 号：R816.5[医药卫生—放射医学]