老年不稳定心绞痛合并抑郁及其治疗  

Depression and treatment in aged patients with unstable angina

作　　者：邱忠霞[1] 马贺军[1] 王涤非[1] 

机构地区：[1]中国医科大学第一附属医院老年病科,辽宁沈阳110001

出　　处：《心血管康复医学杂志》2005年第4期313-315,共3页Chinese Journal of Cardiovascular Rehabilitation Medicine

摘　　要：目的:观察抗抑郁治疗对老年不稳定心绞痛伴抑郁患者近期预后的影响。方法:68例老年不稳定心绞痛伴抑郁患者被随机分为抗抑郁治疗组和心绞痛对照组,各34例。在常规心绞痛药物治疗基础上,治疗组给予心理治疗及抗抑郁药物左洛复(舍曲林)50 mg/d,顿服,疗程8周。结果:治疗组与对照组比较,心绞痛复发率及急性心肌梗死率明显降低,心肌缺血明显改善,P 均<0. 05。结论:抗抑郁治疗能明显改善老年不稳定心绞痛患者的近期预后。Objective：To investigate the efficacy of Zoloft treating depression in aged patients with unstable angina pectoris （UAP）. Methods：A total of 86 aged UAP patients accompanied depression were divided equally into UAP control group and Zoloft group. UAP control group was given commercial drugs. Zoloft group was given both commercial drugs and Zoloft （50 mg, 1 time/d, 8 weeks）. Results： The incidence rates of angina and AMI of UAP group were significantly decreased than those in control group （P〈0.05 all）. Conclusion： Zoloft is effective in improving shortterm prognosis in aged patients with unstable angina pectoris.

关 键 词：心绞痛 抑郁 左洛复 

分 类 号：R541.409[医药卫生—心血管疾病]