上海西南地区儿童肺炎非细菌病原研究  

Study on Non-Bacteria Etiology of Pneumonia in Shanghai Southwest Area

作　　者：刘引[1] 王子才[1] 徐昀[1] 胡润芳[1] 袁芳[1] 夏慧芬[2] 

机构地区：[1]上海市交通大学附属第六人民医院儿科,上海200233 [2]上海市交通大学附属第六人民医院资料室,上海200233

出　　处：《实用儿科临床杂志》2005年第8期769-770,共2页Journal of Applied Clinical Pediatrics

摘　　要：目的了解上海西南地区12岁以下肺炎患儿的病原状况,探讨不同病原致儿童肺炎的不同临床特征.方法采集2002年7月～2004年12月因肺炎住我院儿科的187例患儿血清,应用间接免疫荧光法检测8种常见呼吸道病毒病原体和3种肠道病毒的抗体:呼吸道合胞病毒(RSV)、腺病毒3(ADV3)、流感病毒(IFV)A和B型、副流感病毒(PIV)1～4型、柯萨奇病毒A(CoxA)1、7型、埃可病毒(ECHO)7型的特异型IgM抗体.利用致敏粒子与人血清肺炎支原体(MP)抗体发生凝集反应的原理,检测MP抗体.结果 1.在8种常见呼吸道病毒感染中90例阳性(48.13%),其中RSV阳性最多为37例(19.79%),其次为流感病毒B型31例(16.58%).2.检出MP抗体阳性154例,占肺炎患儿总数的14.21%.结论 RSV是上海西南地区冬春季节婴幼儿肺炎的主要病原.MP已成为学龄期儿童肺炎的重要致病原.Objective To explore the non-bacteria etiology of pneumonia in children under 12 years old in southwest Shanghai,and investigate clinical characteristic of pneumonia caused by different pathogens. Methods The serum of 187 children with pneumonia from July 2002 to December 2004 in hospital were investigated for respiratory syncytial virus（RSV）, adenovirus 3 influenza viruses（IFV） A and B, parainfluenza viruses（PIV）type 1,2,3,4 and coxsackievirus A 1.7 ,echovirus 7 by employing the indirect immunofluorescence assay（IFA）for the identification of nearly 8 different viruses,and 3 different enteroviruses. Based on the principle that sensitized particles were agglutinated hy the pressence of antibodies to mycoplasma pneumonia in human serum. Results Examination for 8 kinds of conventional respiratory virus infected, a total of 90 positive resuhs in 187 cases （48.13%）, Firstly was RSV （19.79%）,secondly was IFV B（16.58%）. Out of these 1084 children, 154 cases（14.21%）showed positive in anti-mycoplasnm a pneumonia. Concluslons RSV is still the leading cause of pneumonia in children during winter and spring in southwest in Shanghai. Mycoplasma pneumonia is having been the major pathogens of the school-aged children with pneunonia.

关 键 词：儿童 肺炎 非细菌病原体 

分 类 号：R725.6[医药卫生—儿科]