22例肺结核化疗期类赫氏反应的临床分析  

Herxheimer-like Reaction in the Chemotherapy of Pulmonary Tuberculosis

作　　者：周东河 朱建芸[2] 

机构地区：[1]广东省南雄市人民医院,南雄512400 [2]中山大学附属第三医院,广州510630

出　　处：《热带医学杂志》2005年第5期720-721,共2页Journal of Tropical Medicine

摘　　要：目的探讨肺结核化疗期类赫氏反应的临床特征和治疗对策。方法回顾分析22例肺结核化疗期类赫氏反应情况。结果此反应发生于痰检阳性的肺结核初治病人,伴有痰菌阳性转阴,胸部X线表现主要渗出性病灶,部分病例有高热、气促、淋巴结肿大和胸腔积液。结论鉴别肺结核治疗中发生的类赫氏反应与耐药结核的真性恶化有重要的临床意义。Objective To study the clinical feature of herxheimer-like reaction in the treatment of tuberculosis.Method Medical records of tuberculosis patients who have herxheimer-like reaction were analyzed retrospectively.Result This reaction occurred in the initial therapy of the tuberculosis cases with positive sputum test. Following conversion from a positive to a negative sputum test, there are manifestations of the radiographic changes, most of which being pulmonary infdtrates. Some patients have high fever, dyspnea, lymph node enlargement or hydrothorax.Conclusions It is important to diagnose for the herxheimer-like reaction during chemotherapy of pulmonary tuberculosis and separate them from drug resistant tuberculosis.

关 键 词：肺结核 类赫氏反应 鉴别 

分 类 号：R521[医药卫生—内科学]