舒痉胶囊中甘草次酸的含量测定研究  

Determination of glycyrrhetinic acid in Shujing capsule by HPLC

作　　者：张莲珠[1] 李海松[1] 吕雪峰[1] 李海日[1] 王本祥[1] 

机构地区：[1]吉林天药科技股份有限公司天然药物研究所,吉林长春130012

出　　处：《中国现代应用药学》2005年第4期313-314,共2页Chinese Journal of Modern Applied Pharmacy

摘　　要：目的建立舒痉胶囊中甘草次酸含量测定的方法。方法采用HPLC,色谱条件:流动相:甲醇-0.05%磷酸(90∶10),检测波长:250nm。结果含量测定平均回收率为98.6%(n=5),RSD为0.53%。结论建立的方法用于舒痉胶囊中甘草次酸含量测定,快速,准确,重现性好。OBJECTIVE To establish a method for determination of glycyrrhetinic acid contents in Shujing capsule. METHODS HPLC was used, using methanol -0.05% phosphoric acid （90： 10） as mobile phase, detected at 250nm. RESULTS The average recovery was 98.6% , and the RSD was 0.53% （ n = 5）. CONCLUSION The method is accurate and can be used in the determination of glycyrrhetinic acid in Shujing capsule.

关 键 词：舒痉胶囊 甘草次酸 含量测定 高效液相色谱法 

分 类 号：R927.2[医药卫生—药学]