肌腱-骨块自体复合移植物嵌压固定法重建前交叉韧带的实验研究  

Experimental research of anterior cruciate ligament reconstruction using press-fit fixation and bone-patellar tendon autograft

作　　者：周密[1] 刘玉杰[1] 陈桂明[1] 田月[1] 赵斌[1] 贾金鹏[1] 

机构地区：[1]解放军总医院骨科,北京100853

出　　处：《中国矫形外科杂志》2005年第16期1248-1251,共4页Orthopedic Journal of China

摘　　要：[目的]研究肌腱-骨块自体移植物嵌压固定法重建前交叉韧带的组织形态学转归。[方法]以8只山羊膝关节为实验模型,用阶梯状联合钻1次成形建立股骨隧道呈倒置瓶颈状,以髌腱-胫骨结节骨块为移植物,在股骨隧道内行嵌压固定;在胫骨端骨桥打结固定。术后4、8、12和16周取材,分别进行放射学、大体形态和组织切片检查,观察隧道宽度变化及移植物的组织学转归。[结果]术后各时间点放射检查未见隧道扩大;HE染色检查显示12周后有明显的腱-骨连接形成,移植骨块与隧道形成骨性愈合。[结论]嵌压固定法重建前交叉韧带有利于移植物的愈合。[Objective] To discuss the histological changes of anterior cruciate ligament reconstruction using bone-patellar tendon autograft with press-fit fixation. [ Method] Eight goats were chosen as the animal models. A customized reamer was used to built the bottleneck-like femoral tunnel and the patellar tendon-tibial tuberosity bone block was cut and fixed as the autograft. Knot was tied on the tibial bony bridge. Animals were killed at 4,8,12, and 16 weeks postoperatively. Radiological , macromorphologi-cal ,and histological investigations were done. [ Result] Radiological studies didn＇ t find evidence of enlargement of the bone tunnel. Histological studies showed obvious bone-tendon ingrowth and bone block-tunnel incorporation 12 weeks postoperatively.[ Conclusion] Anterior cruciate ligament reconstruction using press-fit fixation and bone-patellar tendon autograft exhibited satisfied biological fixation results.

关 键 词：前交叉韧带 嵌压固定 肌腱-骨块自体移植物 组织学 复合移植物 自体移植物 植骨块 固定法 嵌压 实验研究 

分 类 号：R687.3[医药卫生—骨科学]