生殖器疱疹患者尿道和宫颈HSV感染的研究  

The detection of HSV infection in cervix and male urethra in genital herpes patients

作　　者：郑占才[1] 谷巧凤 张晓宁[1] 

机构地区：[1]北京中日友好医院皮肤科,100029 [2]山东莘县人民医院,252400

出　　处：《中国麻风皮肤病杂志》2005年第8期600-601,共2页China Journal of Leprosy and Skin Diseases

摘　　要：目的:了解生殖器疱疹(GH)患者伴发宫颈和男性尿道单纯疱疹病毒(HSV)感染情况,进一步探讨HSV和非淋菌性尿道炎/宫颈炎(NGU)的关系。方法:用HSV聚合酶链反应(PCR)方法检测了56例GH患者的宫颈和男性尿道拭子标本。结果:56例患者中HSVPCR检测阳性共5例,阳性率为8.93%(5/56)。20例女性生殖器疱疹患者宫颈HSVPCR检测阳性率为25.0%(5/20);36例男性GH患者尿道HSVPCR检测结果均为阴性。结论:生殖器疱疹患者伴发女性宫颈HSV感染更为常见,而伴发男性尿道HSV感染相对少见。HSV感染可能是非淋菌性尿道炎/宫颈炎的一个致病因子,在女性宫颈炎的发病中可能更有意义。Objective： To identify the frequency of cervical and male urethral HSV infection in genital herpes patients, and to investigate the possible pathogenic rnle of HSV in nongonococcal urethritis/cervicitis. Methods： Polymerase chain reaction （PCR） was employed to detect HSV DNA in the cervical and male urethral specimens obtained from 56 genital herpes patients. Results： HSV DNA was detected in 5 patients accounting for 8.93% （5/65）. All of the above 5 cases were female, and the positivity rate in female patients was 25% （5/25）. All the 36 male patients showed negative results in the HSV PCR test. Conclusion： In genital herpes patients, the complicated female cervical HSV infection is more common than male urethral HSV infection. HSV can be a causative agent in nongonococcal urethritis/cervicitis, and its role may be more significant in women than in men.

关 键 词：单纯疱疹病毒 生殖器疱疹 聚合酶链反应 女性生殖器疱疹 HSV感染 男性尿道 女性宫颈 聚合酶链反应(PCR) 患者 非淋菌性尿道炎 

分 类 号：R752.1[医药卫生—皮肤病学与性病学] R373.9[医药卫生—临床医学]