山东省157例复发性急性胰腺炎病因和复发特征分析  

Etiology and features of recurrent acute pancreatitis in teen cites of Shandong Province

作　　者：高艳景[1] 李延青[1] 黄柳业 李森林[3] 曾宪中[4] 王青[5] 王福贤[6] 袁圣安 刘春安[8] 李国庆[9] 马骥 

机构地区：[1]山东大学齐鲁医院消化内科,山东济南250012 [2]烟台市毓磺顶医院消化内科,山东烟台264000 [3]聊城市人民医院消化内科,山东聊城252000 [4]临沂市人民医院消化内科,山东临沂276000 [5]青岛市立医院消化内科,山东青岛266011 [6]菏泽市立医院消化科,山东菏泽274014 [7]淄博市中心人民医院消化内科,山东淄博255036 [8]滕州市中心人民医院消化内科,山东滕州277500 [9]潍坊市人民医院消化内科,山东潍坊261041 [10]济宁市人民医院消化内科,山东济宁272111

出　　处：《山东大学学报（医学版）》2005年第7期605-608,共4页Journal of Shandong University:Health Sciences

摘　　要：目的:探讨复发性急性胰腺炎的病因学和复发特点。方法:回顾分析1992年1月～2002年12月间山东省10地市157例复发性急性胰腺炎,将每个病人资料以统一的标准格式进行记录、整理和分析。结果:157例复发性急性胰腺炎中,男性占63%,女性占37%,平均年龄41岁(13～82岁)。胆道结石和酒精为常见的病因,均为20.4%,其次为饮食因素(高脂饮食、暴饮暴食)占13.4%、高血脂症8.3%、胆系感染5.7%、其它原因占5.1%、特发性占26.8%。复发病因男性中酒精占第一位(30.3%),女性胆道结石占第1位(34.5%)。复发1次者占79.6%。并发症出现频率依次为胰腺假性囊肿、腹腺炎和腹水、多脏器功能衰竭、2型糖尿病、休克等。结论:复发性急性胰腺炎是一常见疾病,胆道结石和酒精是其常见病因,不明病因者仍占相当比例。Objective： To explore the etiology and recurrent feature of recurrent acute pancreatitis. Methods： Hundred fifty seven patients with recurrent acute panereatitis were selected from a total 1471 cases of acute pancreatitis in teen cites of Shandong Province from January, 1992 to December, 2002. Data for each patient was recorded on a standardized form. Results： Of the 1471 with acute pancreatitis, 157 （10.7%） had recurrent acute pancreatitis. The majority （63%） was real, with a mean age of 41 yr （range 13-82 yr）. Regarding etiology in recurrent acute pancreatitis, alcohol （20.4%） and cholelithiasiss （20.4%） were the most frequent factor, followed by diet factor （13.4%）, hyperlipemia 8.3%, biliary tract infection 5.7%, other factors （5.1%）, and idiopathic factor （26.8%）. But alcohol as etiology ranked first in male （30.3%） and cholelithiasis ranked first （34.5%） in female. The majority of patients （79.6%） presented with their second attack of pancreatitis. The complications of recurrent acute pancreatitis were pancreatic pseudocyst, ascites and peritonitis, MOF, DM-2 and shock according to their frequencies. Conclusion： Recurrent acute pancreatitis remains a frequent disease, with cholelithiasis and alcohol being the most frequent etiological factors. Alcohol has arisen to the first etiological factor in man. In about 26.8% of cases, the etiology of RAP remains unknown.

关 键 词：胰腺炎 复发 病因学 

分 类 号：R657.51[医药卫生—外科学]