7份血清HIV抗体的不同初筛结果分析  

The Analysis of Different Screening Results of Seven Serum HIV Antibody

作　　者：杨朝军[1] 张光彩[1] 闫文云[1] 杨莉[1] 施玉华[1] 苏莹珍[1] 杨榆玲[1] 

机构地区：[1]云南省疾病预防控制中心,云南昆明650022

出　　处：《中华综合临床医学杂志（北京）》2005年第8期28-29,共2页chinese journal of composite clinical medicine

摘　　要：目的与方法：不同初筛试剂检测HIV抗体出现不同的结果给艾滋病的诊断带来了困惑，通过分析这些样本和试剂，寻找解决这个问题的办法。结果：用梅里埃试剂和雅培快速试剂对2005年5-6月份送检样本进行检测，发现7份样本存在不同的初筛结果。结论：不同的试剂有不同的敏感性和特异性；某些个体的自身抗体与HIV有交叉反应，这些因素会导致初筛结果不一致。选择敏感性和特异性较高并且相差不大的两种试剂可以减少上述情况的发生。Objective and Methods： Different HIV antibody screening results by different screening kits bring confusion. It is needed to find a way to settle the problem by analysis of the serum and kits.Results：Seven serum have different screening results by BioMerieux kit and Abbott instant kit. Conclusion：Different screening kits have different sensitivity and specificity.Some persons have self-antibody reactive with HIV antigen. These factors can lead to different screening results. The problem can be partly settled by selecting two kits with high and similar sensitivity and specificity.

关 键 词：血清 HIV抗体 初筛实验 爱滋病病毒 交叉反应 自身抗体 

分 类 号：R512.91[医药卫生—内科学] R446[医药卫生—临床医学]