睡眠剥夺对大鼠行为和脑电图的影响  

EFFECTS OF SLEEP DEPRIVATION ON BEHAVIOR AND EEG IN RAT

作　　者：丁朝阳[1] 窦兰君[1] 

机构地区：[1]军事医学科学院卫生学环境医学研究所

出　　处：《解放军预防医学杂志》1995年第6期430-433,共4页Journal of Preventive Medicine of Chinese People's Liberation Army

摘　　要：本实验采用小站台、水环境技术和电极埋藏法，观察睡眠剥夺对大鼠行为和脑电图（ＥＥＧ）的影响。结果表明，睡眠剥夺１０天左右，大鼠出现瞌睡、精神萎糜、反应迟钝、全身衰竭，直至死亡。大鼠的ＥＥＧ分析结果表明，睡眠剥夺前θ频带占优势，睡眠剥夺７２ｈ后，频带占优势，差异显著（Ｐ＜０．０１）。说明睡眠剥夺后频带慢移。ＥＥＧ频带的变化，可作为睡眠剥夺引起精神疲劳的客观评价指标。he effects of sleep deprivation(SD)on behavior and EEG in rats were investigated in this experiment with the use ofplatform, water ellviron-ment technique and electrodes implanted method. The resuIts indicated that the rats displayed sleepiness, listlessness, reaction delay’body exhaustion and even death during nearly ten days SD,The resuIts of EEG analyses showed that 6 frequency band predominated before SD,however,after 72h SD frequency band predominated.The statistical differences were signifi cant (P<0.0i),It illustated that the EEG frequency band turned into slowness after SD。 The clianges of EEG frequency bands can be regarded as the objective index of SD-induced mental fatigue。

关 键 词：睡眠 脑电图 行为学 大鼠 精神疲劳 

分 类 号：R338.63[医药卫生—人体生理学]