国产0.125%左旋布比卡因与0.2%罗哌卡因用于术后硬膜外镇痛效果比较  

Effectiveness of 0.125% levobupivacaine and 0.2% ropivacaine in postoperative epidural analgesia: A comparative study

作　　者：高晓枫[1] 罗德兴[1] 林子波[1] 易仁合[1] 纪浩聪[1] 

机构地区：[1]惠州市中心人民医院麻醉科,广东惠州516001

出　　处：《黑龙江医药科学》2005年第4期27-28,共2页Heilongjiang Medicine and Pharmacy

摘　　要：目的:研究0.125%左旋布比卡因行病人硬膜外自控镇痛(PCEA)临床效果,并于0.2%罗哌卡因比较。方法:选择40例择期下腹部手术患者,ASA～级,采用随机双盲法分为两组:左旋布比卡因组(L组,n=20)、罗哌卡因组(R组,n=20)。两组术后分别采用0.125%左旋布比卡因、0.2%罗哌卡因复合小剂量吗啡(0.005%)和地塞米松10mg行病人自控硬膜外镇痛(PCEA),观察两组术后镇痛效果、运动阻滞程度和副作用的发生情况。结果:两组术后视觉模拟评分(VAS)、改良Bromage评分和病人自评镇痛效果满意度比较差异均无显著性(P>0.05)。两组不良反应发生率差异无显著性(P>0.05)。结论:0.125%左旋布比卡因复合小剂量吗啡和地塞米松用于病人术后硬膜外自控镇痛可取得和罗派卡因同样的镇痛效果。Objective： To compare the clinical effectiveness of O. 125% levobupivacaine and 0. 2% ropivacaine in postoperative epidural analgesia. Method ： Forty patients （ASA Ⅰ to Ⅱ ） scheduled for elective hypogastrium surgery were randomly dlvided into levobupivacaine and ropivacaine groups to receive postoperative cpidural analgesia： levobupivacaine group （L group） and ropivacaine group （R group）. Low dose morphine and dexamethasone were added to both groups. The effectiveness of postoperative analgesia , degree of motor block and side--effects of two groups were observed. Result： There were no significant differencs in Visual pain scores （VAS）, modified Bromage scale , patient satisfaction level and side- effects （P 〉 0.05 ）. Conclusions： The effectiveness of 0. 125% levobupivacaine combined with low dose morphine and dexamethasone is satisfactory and reliable .

关 键 词：左旋布比卡因 罗哌卡因 术后硬膜外自控镇痛 

分 类 号：R614.42[医药卫生—麻醉学]